The Class CC72000 C-C diesel-electrics were introduced in 1967 and rated at 3550hp. They saw use on express passenger trains on various routes. From 2002, 30 locos were re-engined to reduce emissions and renumbered as Class CC72100. Most CC72000 were withdrawn by 2010, CC72100 by 2017.
Class CC72100 were SNCF's last big passenger diesels, capable of 160km/h and powered by 2650kW/3550hp engines. They also had a lower gear ratio which could be selected on steeply graded lines or for freight work. By 2013 the CC72100s were limited to a few trains on the Paris - Belfort route and would shortly be replaced by new bi-mode units.